Friday, January 31, 2014

What Is Schizophrenia?

9:18 AM

A long-term mental disorder of a type involving a breakdown in the relation between thought, emotion, and behaviour, leading to faulty perception, inappropriate actions and feelings, withdrawal from reality and personal relationships into fantasy and delusion, and a sense of mental fragmentation.
Patient with schizophrenia disorder may hear voices other people don't hear. They may believe other people are reading their minds, controlling their thoughts, or plotting to harm them. This can terrify people with this illness and make them extremely agitated. Schizophrenic patient may not make sense when they talk. They may sit for hours without moving or talking. Sometimes they seem perfectly fine until they talk about what they are really thinking.
Causes
1.      Genes & Environment Factors:
Scientists have long known that schizophrenia runs in families. The illness occurs in 1 percent of the general population, but it occurs in 10 percent of people who have a first-degree relative with the disorder, such as a parent, brother, or sister. The risk is highest for an identical twin of a person with schizophrenia. He or she has a 40 to 65 percent chance of developing the disorder. We inherit our genes from both parents. Scientists believe several genes are associated with an increased risk of schizophrenia, but that no gene causes the disease by itself.  In addition, it probably takes more than genes to cause the disorder. Scientists think interactions between genes and the environment are necessary for schizophrenia to develop.
Many environmental factors may be involved, such as
·        Exposure to viruses or
·        Malnutrition before birth,
·        Problems during birth,

2.      Brain Chemistry & Structure:
Scientists think that an imbalance in the complex, interrelated chemical reactions of the brain involving the neurotransmitters dopamine and glutamate, and possibly others, plays a role in schizophrenia. Neurotransmitters are substances that allow brain cells to communicate with each other. Scientists are learning more about brain chemistry and its link to schizophrenia. Studies of brain tissue after death also have revealed differences in the brains of people with schizophrenia. Scientists found small changes in the distribution or characteristics of brain cells that likely occurred before birth. Some experts think problems during brain development before birth may lead to faulty connections. The problem may not show up in a person until puberty. The brain undergoes major changes during puberty, and these changes could trigger psychotic symptoms. Scientists have learned a lot about schizophrenia, but more research is needed to help explain how it develops.
Who Is At Risk?
Schizophrenia affects men and women equally. It occurs at similar rates in all ethnic groups around the world. Symptoms such as hallucinations and delusions usually start between ages 16 and 30. Men tend to experience symptoms a little earlier than women. Most of the time, people do not get schizophrenia after age 45. Schizophrenia rarely occurs in children.
Signs & Symptoms:
The symptoms of schizophrenia fall into three broad categories:
1)     Positive symptoms,
2)     Negative symptoms,
3)     Cognitive symptoms.
Positive symptoms: are psychotic behaviours not seen in healthy people. Patients with positive symptoms often "lose touch" with reality. They include the following:
1)     Hallucinations
A patient sees, hears, smells, or feels that no one else can see, hear, smell, or feel. "Voices" are the most common type of hallucination in schizophrenia. Many people with the disorder hear voices. The voices may talk to the person about his or her behaviour, order the people to do things, or warn the person of danger. Sometimes the voices talk to each other. Other types of hallucinations include seeing people or objects that are not there, smelling odours that no one else detects, and feeling things like invisible fingers touching their bodies when no one is near.
2)     Delusions
False beliefs that are not part of the person's culture and do not change. The person believes delusions even after other people prove that the beliefs are not true or logical. People with schizophrenia can have delusions that seem bizarre, such as believing that neighbours can control their behaviour with magnetic waves. They may also believe that people on television are directing special messages to them, or that radio stations are broadcasting their thoughts aloud to others. They may have paranoid delusions and believe that others are trying to harm them, such as by cheating, harassing, poisoning, spying on, or plotting against them or the people they care about. These beliefs are called "delusions of persecution."
3)     Thought disorders
 Are unusual or dysfunctional ways of thinking. One form of thought disorder is called "disorganized thinking." This is when a patient has trouble organizing his or her thoughts or connecting them logically. They may talk in a garbled way that is hard to understand. Another form is called "thought blocking." This is when a person stops speaking abruptly in the middle of a thought. When asked why he or she stopped talking, the patient may say that it felt as if the thought had been taken out of his or her head.
4)     Movement disorders
It may appear as agitated body movements. A patient with a movement disorder may repeat certain motions over and over. In the other extreme, a person may become catatonic. Catatonia is a state in which a patient does not move and does not respond to others.
Negative symptoms: are associated with disruptions to normal emotions and behaviours. These symptoms are harder to recognize as part of the disorder and can be mistaken for depression or other conditions. These symptoms include the following:
1)     Flat affect (a person's face does not move or he or she talks in a dull or monotonous voice)
2)     Lack of pleasure in everyday life
3)     Lack of ability to begin and sustain planned activities
4)     Speaking little.
People with negative symptoms need help with everyday tasks. They often neglect basic personal hygiene. This may make them seem lazy or unwilling to help themselves, but the problems are symptoms caused by the schizophrenia.
Cognitive symptoms: are subtle. Like negative symptoms, cognitive symptoms may be difficult to recognize as part of the disorder. Often, they are detected only when other tests are performed. Cognitive symptoms include the following:
1)     Poor "executive functioning" (the ability to understand information and use it to make decisions)
2)     Trouble focusing or paying attention.
3)     Problems with "working memory" (the ability to use information immediately after learning it).
Cognitive symptoms often make it hard to lead a normal life and earn a living. They can cause great emotional distress.
Treatments
Because the causes of schizophrenia are still unknown, treatments focus on eliminating the symptoms of the disease
1)     Antipsychotic medications
Antipsychotic medications have been available since the mid-1950. The older types are called conventional or "typical" antipsychotics. In the 1990's, new antipsychotic medications were developed. These new medications are called second generation, or "atypical" antipsychotics.
2)     Psychosocial treatments
Psychosocial treatments can help patients with schizophrenia that is already stabilized on antipsychotic medication. Psychosocial treatments help these patients deal with the everyday challenges of the illness, such as difficulty with communication, self-care, work, and forming and keeping relationships. Learning and using coping mechanisms to address these problems allow people with schizophrenia to socialize and attend school and work.
3)     Illness Management Skills.
Patient with schizophrenia can take an active role in managing their own illness. Once patients learn basic facts about schizophrenia and its treatment, they can make informed decisions about their care. If they know how to watch for the early warning signs of relapse and make a plan to respond, patients can learn to prevent relapses.
4)     Integrated treatment for co-occurring substance abuse.
Substance abuse is the most common co-occurring disorder in people with schizophrenia. But ordinary substance abuse treatment programs usually do not address this population's special needs. When schizophrenia treatment programs and drug treatment programs are used together, patients get better results.
5)     Rehabilitation.
 Rehabilitation emphasizes social and vocational training to help people with schizophrenia function better in their communities. Because schizophrenia usually develops in people during the critical career-forming years of life (ages 18 to 35), and because the disease makes normal thinking and functioning difficult, most patients do not receive training in the skills needed for a job.
6)     Family education.
Patients with schizophrenia are often discharged from the hospital into the care of their families. So it is important that family members know as much as possible about the disease. With the help of a therapist, family members can learn coping strategies and problem-solving skills. In this way the family can help make sure their loved one sticks with treatment and stays on his or her medication.
7)     Cognitive behavioural therapy.
 (CBT) is a type of psychotherapy that focuses on thinking and behaviour. CBT helps patients with symptoms that do not go away even when they take medication. The therapist teaches people with schizophrenia how to test the reality of their thoughts and perceptions, how to "not listen" to their voices, and how to manage their symptoms overall.
8)     Self-help groups.
Self-help groups for people with schizophrenia and their families are becoming more common. Professional therapists usually are not involved, but group members support and comfort each other. People in self-help groups know that others are facing the same problems, which can help everyone feel less isolated. The networking that takes place in self-help groups can also prompt families to work together to advocate for research and more hospital and community treatment programs.
How can you help a person with schizophrenia?
People with schizophrenia often resist treatment. They may not think they need help because they believe their delusions or hallucinations are real. In these cases, family and friends may need to take action to keep their loved one safe. Laws vary from state to state, and it can be difficult to force a person with a mental disorder into treatment or hospitalization. But when a person becomes dangerous to himself or herself, or to others, family members or friends may have to call the police to take their loved one to the hospital.
It can be difficult to know how to respond to someone with schizophrenia who makes strange or clearly false statements. Remember that these beliefs or hallucinations seem very real to the person. It is not helpful to say they are wrong or imaginary. But going along with the delusions is not helpful, either. Instead, calmly say that you see things differently. Tell them that you acknowledge that everyone has the right to see things his or her own way. In addition, it is important to understand that schizophrenia is a biological illness. Being respectful, supportive, and kind without tolerating dangerous or inappropriate behaviour is the best way to approach people with this disorder.

Are schizophrenic patient violent?
People with schizophrenia are not usually violent. Most violent crimes are not committed by people with schizophrenia. However, some symptoms are associated with violence, such as delusions of persecution. Substance abuse may also increase the chance a person will become violent. If a person with schizophrenia becomes violent, the violence is usually directed at family members and tends to take place at home. The risk of violence among people with schizophrenia is small. But people with the illness attempt suicide much more often than others. It is hard to predict which patient with schizophrenia is prone to suicide. If you know someone who talks about or attempts suicide, help him or her find professional help right away.
Schizophrenia and smoking
Addiction to nicotine is the most common in people with schizophrenia. They are addicted to nicotine at three times the rate of the general population .The relationship between smoking and schizophrenia is complex. People with schizophrenia seem to be driven to smoke, and researchers are exploring whether there is a biological basis for this need. In addition to its known health hazards, several studies have found that smoking may make antipsychotic drugs less effective. Quitting smoking may be very difficult for people with schizophrenia because nicotine withdrawal may cause their psychotic symptoms to get worse for a while.

Dr. Imtiaz Syed, M.B,B.S, MBA, CRA, PCQI, CPC
Redditch, Gloucestershire. UK.

Ref: National institute of mental health , http://www.nimh.nih.gov/index.shtml

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1 comments:

  1. Never studied schizophrenia in such a detail..that's too knowledgefull.thank you :-)

    ReplyDelete

 

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